About Us

Research Expertise

We take advantage of innovative approaches from a broad remit of disciplines- Transcriptomics, Proteomics, Chemical Biology, Molecular Parasitology, Molecular Vector Biology, Arbovirology, Glycobiology, and Vaccinology, to develop enabling technologies to support studies in vector-borne diseases that hopefully can eventually contribute to elimination and eradication efforts for diseases such as malaria and dengue.  This “Integrative Biology” or “multi-OMICS” approach allows us to finally address critical biological questions in the context of human/vector host-pathogen interactions with respect to malaria and arbovirus transmission biology.  [Yes, we also work on COVID-19 to contribute our skills where possible to fight the pandemic]

Principal investigator

Dr. Rhoel R. Dinglasan, PhD, MPH

Rhoel Dinglasan attended graduate school at Yale University, earning a MPH in Global Health with a concentration in Infectious Disease and the MPhil in Molecular Vector Biology (Dengue transmission/Wolbachia biology), before transferring to the Center for Vaccine Development at the University of Maryland, School of Medicine, to earn a PhD in Microbiology & Immunology, working in the laboratory of Prof. Abdu Azad on Anopheles mosquito glycobiology.  He completed his postdoctoral training at Johns Hopkins Bloomberg School of Public Health in the laboratory of Prof. Marcelo Jacobs-Lorena, before transitioning to a tenure-track Assistant Professor position at Johns Hopkins. He was then recruited to the University of Florida (UF), where he is a full Professor in the Department of Infectious Diseases & Immunology, College of Veterinary Medicine, and the UF Emerging Pathogens Institute.


Making A Global Impact

To support malaria elimination and eradication as well as parallel efforts at controlling arbovirus transmission, the lab is focused on understanding the fundamental biology mediating host-pathogen interactions and translating these scientific insights into novel disease interventions.

Laboratory Overview:
Host-Pathogen Research

Arthropod transmission of pathogens such as the malaria parasite (Plasmodium spp.), dengue virus or Zika virus drives the spread of these pathogens and the diseases that they cause in both endemic and epidemic settings around the Globe.  Our program’s objective is to characterize the drivers of pathogen transmission by mosquitoes at both the molecular and ecological level to fully understand vector host-pathogen dynamics and disease risk in the laboratory and in the field.


 Global Health Innovative Technology Fund
 U.S. Centers for Disease Control and Prevention
PATH-Malaria Vaccine Initiative
 Bill & Melinda Gates Foundation
 Human Frontiers Science Program
 Johns Hopkins Malaria Research Institute
 University of Florida Preeminence Initiative
 University of Florida Emerging Pathogens Institute

Collaborating Institutions

• Armed Forces Research Institute of Medical Sciences,  Thailand
BOKU, Austria
Brown University, USA
Center for Research in Infectious Diseases, Cameroon
Center for Medical, Agricultural, & Veterinary Entomology (CMAVE), ARS-USDA, USA
Centre Pasteur du Cameroun, Cameroon
Centre de Recherches Médicales de Lambaréné (CERMEL), Gabon
 Ehime University, Japan
 Harvard School of Public Health, USA
 Hokkaido University, Japan
 Imperial College of London, UK
 Ifakara Health Institute, Tanzania
 INSP, Cuernavaca, Mexico
Institut Pasteur, France
International Centre for Insect Physiology & Ecology, Kenya
INRB, Democratic Republic of Congo
 IRD Montpellier, France
Johns Hopkins University, USA
 The Jenner Institute, University of Oxford, UK
 Kinki University School of Medicine, Japan
 Kinshasa School of Public Health, Kinshasa, Democratic Republic of Congo
London School of Hygiene & Tropical Medicine, UK
 Laboratory of Malaria & Vector Research, NIAID/NIH, USA
• Mahidol University, Thailand
• Massachusetts Institute of Technology, USA
 Monash University, Australia 
Mercy Research Hospital Laboratory, Sierra Leone
• Muhimbili University of Health & Allied Sciences,

Naval Entomology Center of Excellence, USA
Naval Medical Research Unit-4, Ghana
Naval Medical Research Unit-6, Peru
The Noguchi Memorial Institute for Medical Research, Ghana
• Ohio State University, USA
Oregon Health and Sciences University, USA
Radboud University Nijmegen Medical Center, Netherlands
Redeemer's University (ACEGID), Nigeria
 RMIT University, Australia
Rwanda Biomedical Centre, Rwanda
 Technical University of Munich, Germany
Tübingen University, Germany
University of Dschang, Cameroon
 University of Ghana (WACCBIP), Ghana
University of Glasgow, Scotland
University of Massachusetts Medical School, USA
University of North Carolina at Chapel Hill, USA
University of Miami, USA
University of Milan, Italy
University of Nebraska Medical Center, USA
University of Sciences, Techniques & Technologies of Bamako, Mali
University of South Florida, USA
University of Texas-Medical Branch, USA
 US Naval Research Laboratory, USA
 Vanderbilt University, USA
Vaccine Research Center, NIAID/NIH, USA
 Walter and Eliza Hall Institute for Medical Research,  Australia
• Walter Reed Army Institute of Research, USA

Contact Us

Learn more about the research in the Dinglasan Laboratory.

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Latest News

Stay Up To Date With Our Latest News. Learn About New Developments, Treatments, Vaccines, Our Lab & Much More!
First in human clinical trials of the AnAPN1 malaria transmission-blocking vaccine

Former director of the PATH Malaria Vaccine Initiative, Christian Loucq, M.D., says it is exciting to see Dinglasan's concept moving toward a clinical trial. "There are very interesting issues to be addressed in this project which span the technical, immunological, strategic, regulatory and behavioral," says Dr. Loucq, who also formerly directed the International Vaccine Institute. "A transmission-blocking vaccine would be the most elegant solution to the problem of malaria."

Clustered rapid induction of apoptosis limits ZIKV and DENV-2 proliferation in the midguts of Aedes aegypti

Jasmine's 1st first-author paper (Yay Jasmine!) that dissects very early innate immune defense mechanisms of mosquito vectors following infection with flaviviruses.

UF Professor of Infectious Diseases, Dr. Rhoel Dinglasan, discusses the new saliva COVID tests