Arbovirus Transmission Biology

Arbovirus Transmission Biology

TEAM ARBO team takes advantage of the unique research environment offered by the CDC Southeastern Center of Excellence in Vector Borne Diseases (SEVBD) program to unify epidemiology, entomology, and molecular biology approaches to address pressing and critical state-wide public health needs. They prioritize a supportive and collaborative work culture and strive for excellence in science communication as well as research. We encourage you to visit the CDC Southeastern Center of Excellence in Vector Borne Diseases website to learn more about what our lab does in the context of the center activities: http://cdcsercoevbd-flgateway.org/. TEAM ARBO consists of 4 PhD students, one undergraduate student and 2 postdoctoral associates. One postdoc and PhD student forms a bridge with TEAM MALARIA as well. Together, the team studies the epidemiology and molecular biology of arthropod-borne viruses, primarily focusing on Zika and dengue. Future work will expand to Chikungunya virus and Rift Valley Fever Virus.

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First in human clinical trials of the AnAPN1 malaria transmission-blocking vaccine

Former director of the PATH Malaria Vaccine Initiative, Christian Loucq, M.D., says it is exciting to see Dinglasan's concept moving toward a clinical trial. "There are very interesting issues to be addressed in this project which span the technical, immunological, strategic, regulatory and behavioral," says Dr. Loucq, who also formerly directed the International Vaccine Institute. "A transmission-blocking vaccine would be the most elegant solution to the problem of malaria."

Clustered rapid induction of apoptosis limits ZIKV and DENV-2 proliferation in the midguts of Aedes aegypti

Jasmine's 1st first-author paper (Yay Jasmine!) that dissects very early innate immune defense mechanisms of mosquito vectors following infection with flaviviruses.

UF Professor of Infectious Diseases, Dr. Rhoel Dinglasan, discusses the new saliva COVID tests