Dr. Rhoel Dinglasan

Dr. Rhoel Dinglasan

Rhoel Dinglasan attended graduate school at Yale University, earning a MPH in Global Health with a concentration in Infectious Disease and the MPhil in Molecular Vector Biology (Dengue transmission/Wolbachia biology), before transferring to the Center for Vaccine Development at the University of Maryland, School of Medicine, to earn a PhD in Microbiology & Immunology, completing his doctoral thesis research within two years in the laboratory of Prof. Abdu Azad on Anopheles mosquito glycobiology.  He was a Dmitri V. d’Arbeloff (Millipore Foundation) and NIAID, NIH Ruth L. Kirschstein National Research Scholar Award postdoctoral fellow in the laboratory of Prof. Marcelo Jacobs-Lorena, a renowned expert on mosquito transgenesis and vector host-pathogen interactions at the Johns Hopkins Malaria Research Institute (JHMRI). He joined the Molecular Microbiology & Immunology/JHMRI faculty of Johns Hopkins University as a tenure-track Assistant Professor in February 2009 with a National Institute of Allergy & Infectious Diseases, US National Institutes of Health (NIH) K22 Career Development Award.  

Dinglasan’s research interests include mosquito biology & physiology, pathogenesis, and the application of mass spectrometry-based approaches toward the molecular and cellular analysis of critical transition steps during malaria parasite (human-mosquito-human) transmission.  Importantly, his research program also leverages nanoparticle technology in the development of vaccine and drug delivery systems as well as diagnostics. He was recruited to the University of Florida in late 2015 as part of the UF Preeminence Faculty Initiative as an Associate Professor of Infectious Diseases (Tenured). He joined UF in August 2016 and both his lab and office are located in the UF Emerging Pathogens Institute.  He is the Director of the CDC Southeastern Center of Excellence for Vector Borne Diseases as well as the Associate Chair of Research for the Department of Infectious Diseases & Immunology (primary affiliation) at the UF College of Veterinary Medicine and is affiliated with the Departments of Anatomy & Cell Biology and Molecular Genetics & Microbiology at the UF College of Medicine.  Dinglasan has served as Chair of the Enabling Technologies Consultancy Group for the Malaria Eradication Research Agenda (malERA).  He currently serves on the Editorial Board of PLoS Neglected Tropical Diseases, the Advisory Board for the United States Military MIDRP Malaria Vaccine and Emerging Infectious Diseases Programs and the Scientific Technical Advisory Board of the Wellcome Trust DELTAS program-funded Developing Excellence in Leadership & Genetics Training in Malaria Elimination (DELGEME) in Mali.

Learn more about Dr. Dinglasan, please click here.
Pictured: Dr. Rebecca E. Tweedell (former Hopkins PhD student in the lab)

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First in human clinical trials of the AnAPN1 malaria transmission-blocking vaccine

Former director of the PATH Malaria Vaccine Initiative, Christian Loucq, M.D., says it is exciting to see Dinglasan's concept moving toward a clinical trial. "There are very interesting issues to be addressed in this project which span the technical, immunological, strategic, regulatory and behavioral," says Dr. Loucq, who also formerly directed the International Vaccine Institute. "A transmission-blocking vaccine would be the most elegant solution to the problem of malaria."

Clustered rapid induction of apoptosis limits ZIKV and DENV-2 proliferation in the midguts of Aedes aegypti

Jasmine's 1st first-author paper (Yay Jasmine!) that dissects very early innate immune defense mechanisms of mosquito vectors following infection with flaviviruses.

UF Professor of Infectious Diseases, Dr. Rhoel Dinglasan, discusses the new saliva COVID tests