My research interests are focused on the malaria liver stage, particularly in regards to the mechanism of P. falciparum invasion of the liver. Malaria infection begins with the bite of an infected mosquito that injects parasitic sporozoites into the skin. These sporozoites can make their way from the skin and into the circulation. From there, they migrate to the liver, where they cross the sinusoidal barrier to access the hepatocytes and establish the liver stage of infection. This stage is symptomatically silent but leads to the blood stage, when clinical disease begins.